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Several reports suggest that IFN- decreases hepatic cytochrome expression and activity [2, 3]
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Oral formulations A number of orally administered drugs with poor water solubility were recently reformulated using cyclodextrins
Reducing mtDNA release The pathological release of mtDNA into the cytosol or extracellular spaceoften due to mitochondrial membrane permeabilization or dysfunctionis the initiating event driving mtDNA-induced inflammation
Fanelli, et al
