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Blocking this antioxidant axis with SLC7A11 and GPX4 inhibitors (ferroptosis inducers) such as the small-molecule Erastin and RSL3, respectively, leads to uncontrolled accumulation of lipid peroxides at the plasma membrane and other endomembranes within the cell, which promotes membrane permeabilization, damages membrane integrity and ultimately induces ferroptosis [34, 38]
Stimulatory effect of Silibinin on the DNA synthesis in partially hepatectomized rat livers: non-response in hepatoma and other malign cell lines
Amelioration of cisplatin-induced nephrotoxicity by statins
