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We found that TDP-43 is SUMOylated by SUMO2 in a conserved region of the C-terminal domain at lysine (K) 408 directly adjacent to phosphorylation residues serine (S) 409/410 characteristically phosphorylated in TDP-43 aggregates

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Reconstitution: 2.0 mL water per 5 mg vial gives 2.5 mg/mL for fine low-dose steps