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Description
The instability of hydrazone linkers is presumably caused by their slow hydrolysis under physiological conditions that leads to a progressive release of the drug in circulation and enhanced risk of systemic toxicity
Ethics statement For studies involving human cadaveric material, a waiver was obtained by Johns Hopkins Institutional Review Board
Evolution of SARS-CoV-2: Review of Mutations, Role of the Host Immune System
doi: 10.1016/S0076-6879(08)36001-7
