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Enclomiphene provides the benefits of the trans isomer without these issues

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It forms a heteromer set with the MYC-associated X (Max) factor, which binds to E-boxes in gene promoters [39]
Clin Endocrinol 40:383391 Hansen TB, Brixen K, Vahl N, Jrgensen JO, Christiansen JS, Mosekilde L, Hagen C (1996) Effects of 12 months of growth hormone (GH) treatment on calciotropic hormones, calcium homeostasis, and bone metabolism in adults with acquired GH deficiency: a double blind, randomized, placebo-controlled study