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10.1371/journal.pone.0113939 94 NagahisaT.YamaguchiS.KosugiS.HommaK.MiyashitaK.IrieJ.et al (2022)
Because B vitamins are water-soluble and the body can't store most of them long-term, regular intake through food (or supplementation when needed) matters more than occasional big doses
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