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(2016) www.sciencedaily.com From the article: Doctors have long known that men with low testosterone are at greater risk for developing type 2 diabetes

Oxidant stress from nitric oxide synthase-3 uncoupling stimulates cardiac pathologic remodeling from chronic pressure load

injected pharmacological and physiological doses of testosterone into female and castrated male mice and found an upregulation of arginase II and ODC, while ornithine aminotransferase was found to be downregulated [103]

GRX1 deficiency exacerbates COPD progression by elevating TGF- levels, collagen deposition and basal cell plasticity, accelerating lung remodeling (87)