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In nociceptive pain, it is driven by ongoing tissue injury
Christen WG, Liu S, Glynn RJ, Gaziano, JM, Buring JE

The Genetic Factor Although the significance of genetics in congenital cataract is very well established with some three dozen genes identified in which mutations can cause human cataract, 7 the role of genetics in aging-related cataract is less well defined

In addition, an intracellular abundance of reduced glutathione, as compared to oxidized glutathione, helps ensure healthy cell function
