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Keywords: angle closure, glaucoma, drug-induced, iatrogenic Introduction Acute angle closure glaucoma is an ophthalmic emergency

17 This process appears to be vascular endothelial growth factor (VEGF)-dependent, as inhibiting VEGF wipes out the antidepressant effects of ketamine and administration of VEGF into the prefrontal cortex reproduces the positive effects seen with ketamine

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Therapeutic Perspectives and Challenges Although most therapeutic approaches put to test against LC have targeted symptom alleviation [307], a comprehensive evaluation of symptoms and clinical signs of affected patients is imperative, in order to timely recognize red flag features pointing towards underlying objective systemic disorders that are likely to have a decisive impact on patient prognosis