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One cause of such a cytokine storm is an imbalance of the ratio between ACE1 (the pro-inflammatory mediator) and ACE2 (the anti-inflammatory mediator)
Furthermore, the design of unstructured and structured models of the bioprocess has allowed development of novel optimization strategies, closing the iteration-cycle between the in silico and in vivo approaches of analysis of this biotransformation process
Parvanova et al
& Bhosle, R
