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See below, Patients with Known or Suspected Mitochondrial Disease. Experience has indicated that children under the age of two years are at a considerably increased risk of developing fatal hepatotoxicity, especially those with the aforementioned conditions

For instance, RARs can enhance the expression of sterol regulatory element-binding protein 1c (SREBP-1c), a key transcription factor that stimulates lipogenesis

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2019;10(10):e00078