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At the molecular level, IAA causes neurotoxicity by reducing mitochondrial membrane potential, aggravating oxidative stress and DNA damage

In addition, plasma TMAO was an independent predictor in CHD patients (n = 423) with or without type 2 diabetes mellitus (T2DM) (Yu et al., 2019)

Changes in genetics encompass MET exon 14 skipping mutations (METex14), amplification of MET genes, increased c-MET protein levels, structural domain mutations in MET kinase, and fusion of MET genes [22]
