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Description
Jour Clin Med Res
Mutant isocitrate dehydrogenase 1/2 (IDH1/2) produces the oncometabolite 2-hydroxyglutarate (2-HG), which inhibits -KGdependent dioxygenases, resulting in widespread epigenetic dysregulation [98-100]
Cupertino RB, Soheili-Nezhad S, Grevet EH, Bandeira CE, Picon FA, Tavares MEA, et al
[DOI] [Google Scholar] 40.Villalobos-Pezos M., Muoz-Faria O., Ah-Hen K.S., Garrido-Figueroa M.F., Garca-Figueroa O., Gonzlez-Esparza A., de Medina L.G.-P., Bastas-Montes J.M
