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Non-motor symptoms in Parkinson's disease encompass a variety of functions, such as disturbances in sleep-wake cycle regulation, cognitive dysfunction (such as frontal executive dysfunction, memory retrieval problems, dementia, and hallucinations), mood and affect disorders, autonomic dysfunction (primarily orthostatic hypotension, urogenital dysfunction, constipation, and excessive sweating), sensory symptoms (especially reduced sense of smell), and pain

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In the heart, this can manifest as reduced contractility and impaired cardiac function, while in the brain, it may contribute to neuronal dysfunction and cognitive decline