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In the subsequent differential expression analysis, while the vehicle-treated groups (i.e., WT-Glargine vs KO-Glargine) failed to reveal any meaningful differences in their phosphoproteome profiles (Supplementary Fig
In Figure 4 I show how the LogD varies with pH for two acidic and two basic drugs
GPX4 does not follow MichaelisMenten kinetics, likely because the rate-limiting step during this mechanism is the binding of the initial peroxide to the GPX4 active site, rather than the elimination of the GPX-substrate complex
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