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Approximately 10 patients with LS have been identified with pathogenic SDHB variations, most exhibiting neurodegenerative symptoms, seizures, and dystonia, with one patient showing heat sensitivity (72)

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C.AbasF.et al (2021)

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Yang D, Wang X, Zhang L et al (2022) Lipid metabolism and storage in neuroglia: role in brain development and neurodegenerative diseases

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