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In addition to serving as a primary component of cellular membranes and binding sites for intra- and intercellular proteins, some glycerophospholipids in eukaryotic cells, such as phosphatidylinositols and phosphatidic acids are either precursors of or, themselves, membrane-derived second messengers

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591 The cyclic guanosine monophosphateadenosine monophosphate (i.e., GMP-AMP) synthase-stimulator of interferon genes (cGAS-STING) signaling pathway is a fundamental system involved in the innate and adaptive immune response to infection and inflammation
