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Researchers studying combined-compound protocols often investigate the three blend components together

Increasing levels of VitB12 in humans have been shown to lead to a decline in 24-h mean melatonin levels and nocturnal melatonin levels during bright-light exposure, thereby disrupting the sleep-wake cycle toward increased alertness and decreased sleep duration [21, 38]

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Most of the vitamins we need cannot be synthesised or made within our bodies, so we get the majority from our diet and the foods we eat, some of which are fortified in the modern era, with extra vitamins added to products