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Understanding the structure and function of catalases: Clues from molecular evolution and in vitro mutagenesis
Press, Oxford, UK, 1994)
10.1111/j.1067-1927.2005.130211.x 34 DalirfardoueiR.JamialahmadiK.JafarianA
120 ROS play crucial modulatory roles in amplifying distal TCR pathways, including Ca 2+ -calcineurin-NFAT, IKK-NF-B, Ras-ERK1/2, and mTOR cascades, which in turn enhance T-cell activation, proliferation, and cytokine production (e.g., IL-2)
