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Option 2 - In-collection derivatization: Add NEM directly to biological fluids (plasma, saliva, urine) during collection to achieve a final concentration of 10 mM [25]

Some studies enrolled participants from all age groups, with Bhattacharya and Swarup-Mitra 33 and Ozojiofor et al

This enzymatic activity gave origin to the alternative name of ADH5, GSNOR, proposing it is a protein denitrosylase that can modulate the level of S-nitrosylations by reducing GSNO 48