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In zebrafish models, PEMFs increased the expression of key melanin synthesis enzymes, such as tyrosinase-related protein 1 (TRP1) and dopachrome tautomerase (DCT), through ERK and p38 phosphorylation pathways
DRG-specifically enriched lncRNA (DS-lncRNA) highly expressed in DRG neurons was significantly downregulated following L4 SNL, CCI, or axotomy of the unilateral sciatic nerve, increasing the expression of Ehmt2 /G9a triggered by the transcription cofactor RALY/RNP II, which correspondingly reduced the expression of opioid receptors and Kcna2 in related DRGs, contributing to NP [112]
& Vilen, B
CXCR4 inhibition counteracts immunosuppressive properties of metastatic NSCLC stem cells
