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By contrast, in patients with stroke due to cardiac embolism, interaction analysis revealed that bridging IVT was linked to a 60% lower likelihood of successful reperfusion at any time point when distal thrombus migration was detected on repeated vessel imaging (adjusted HR 0.4

Collectively, these studies indicated that the functions of occludin are complex, and the mechanism by which occludin regulates the tight junction should be investigated in great detail

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