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A separate trial with an active comparator group was deemed to be necessary for patients with HCV genotype 3 in light of the special clinical challenges presented in this population
About 90% of patients experience a prodromal phase (63), that is characterized mainly by signs and symptoms of autonomic dysfunction such as pallor, sweating, lethargy, hot flashes and rarely temperature change and drooling (65)
In vitro findings showed antioxidant activity, strong collagenase inhibition, increased Type I collagen production, and enhanced expression of hyaluronan synthase proteins linked to skin hydration
