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Lithiums neuroprotective properties in AD by acting on multiple neuropathological targets, such as reducing amyloid deposition and tau phosphorylation, enhancing autophagy, neurogenesis, and synaptic plasticity, regulating cholinergic and glucose metabolism, inhibiting neuroinflammation, oxidative stress, and apoptosis, while preserving mitochondrial function

As a decline in inflammation and oxidative stress occurred, a concomitant decrease in Nrf2 activation likely followed

Int J Lab Hematol 32:139141 Farias MG, Schunck EG, Dal B S, de Castro SM (2010) Definition of reference ranges for the platelet distribution width (PDW): a local need
Badiye , Nayereh Baghcheghi , Nasser Bagheri , Sara Bagherieh , Saeed Bahadory , Atif Amin Baig , Mohan Bairwa , Jennifer L
