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Higher NAD enhances SIRT1 activity, promoting fat oxidation and mitochondrial remodeling via PGC-1 pathwaysmechanisms consistent with improved endurance and recovery potential (Cant et al., Cell Metabolism
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Originally developed in the 1990s, as a fat burning (lipolytic) compound, AOD9604 stimulates the breakdown or destruction of fat cells (lipolysis) and inhibits the metabolic formation of fat (lipogenesis) in animal studies

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