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Diabetologia (2017) 60(9):156676
Attempting to continue use can lead to internal short circuits

Deliver triglycerides from the liver to muscle and adipose tissue Converted into IDL and eventually LDL after triglyceride removal Important in maintaining energy supply during fasting Elevated VLDL levels are commonly associated with hypertriglyceridemia
doi: 10.1200/JCO.2008.19.2435 87 BertrandAKostineMBarnetcheTTruchetetMESchaeverbekeT