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DOI: 10.1159/000369585 31

Only one AdoMet-dependent methyltransferase gene, CRG1 , was found to be altered in its expression between the sam1 -deficient strain and wildtype, being upregulated 1.58-fold (p-value = 0.0236) (Fig 1B)
Accessed 13th June, 2025

For patients with severe depression, drug therapy should be used as the first-line treatment option
