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In the peroxisome proliferator-activated receptor (PPAR)-induced COPD model, upregulation of GPX3 expression can reduce lung tissue damage caused by oxidative stress (Reddy et al., 2018)

Additional natural compounds with potential anti-OSF efficacy include epigallocatechin-3-gallate (EGCG), aloe vera, lycopene, curcumin, and honey

Typical usage concentrations range from 0.5% (where hydration benefits already show up) all the way to 90%+ (where it replaces water as the main base)

The LA-derived 15-LOX metabolite, 13S-hydroperoxyoctadecaenoic acid, has been found to induce apoptosis in colon cancer cells (Shureiqi et al., 2000)