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These observations were performed by three independent physiatrists who were blinded to the treatment groups, ensuring unbiased assessment

Tesofensine as a dopamine transporter uptake inhibitor Unlike traditional appetite suppressants and other drugs meant for managing obesity that act on neuroreceptors located near hunger areas in the brain, tesofensine works as an agent that targets the reuptake of dopamine into neurons, thereby upping this pleasure inducing hormone

The NNMT enzyme it inhibits is constitutively expressed in adipose tissue and liver, meaning timing relative to meals is less critical than consistency