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Carnosinase levels in aging brain: redox state induction and cellular stress response

Figure 8 Discussion A growing evidence has suggested that regulated necrosis could induce numerous inflammation and serves as a therapeutic target of AKI (Lin and Hsu, 2020)

Enzyme replacement treatment (ERT) with recombinant human -Gal A decreased the Gb3 accumulation and oxidative stress, which resulted in amelioration of the deformed cellular structure of the GLA-mutant kidney organoids

Since acidosis is a hallmark of inflammatory processes as well as a crucial determinant of tumor progression, resulting from the increased glycolysis and the subsequent accumulation of lactic acid as well as the massive production of protons [83], glutamine supplementation may help to reduce inflammation in cancer cachexia patients by maintaining pH homeostasis in the body via ammonia (NH 3 ) transport between tissues [5,84]