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Abduraman MA, Azizan NA, Teoh SH et al

In 1990, Morier et al

However, excessive ferroptosis may result in hypoxia, nutrient deprivation, and inflammation-related immunosuppression within the tumor microenvironment (TME), potentially facilitating tumor growth

It also suppresses HIF-1, accompanied by decreased levels of lactate and other important metabolites that are involved in GSH synthesis [219]
