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It is noteworthy that PF-4708671 can inhibit p70S6K1 as shown by the diminished phosphorylation of its downstream target, ribosomal protein S6, even though the level of p70S6K1 phosphorylation increased (Fig

[DOI] [PubMed] [Google Scholar] 185.Christensen K, Rogers E, Green GA, Hamilton DA, Mermelstein F, Liao E, et al
doi: 10.1053/j.jvca.2008.03.007

Hoffman JR, Williams DR, Emerson NS, et al
