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The compound 37 connected through an ether linkage show 713-fold decrease in the inhibitory ability (IC 50 = 378.11 M) indicate the sulfur atom is very important in chelating with the copper ions and contributes in a greater inhibition tyrosinase activity
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6.3 Alcohol Alcoholic liver disease patients have low hepatic and plasma GSH levels due to multiple mechanisms such as oxidative stress, nutritional deficiency and abnormalities in the methionine metabolic pathway that impairs cysteine availability [164166]
[56] The presence of antibodies to gastric parietal cells and intrinsic factor is common in PA
