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JHU-083 markedly suppresses the recruitment of MDSCs by decreasing tumor-derived CSF3 levels via degradation of C/EBP, which in turn increases the numbers of proinflammatory TAMs and enhances antigen presentation to CD8(+) T cells, resulting in stronger T-cell responses 150

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Energy and Vitality Fatigue is a common complaint among many individuals, often due to factors like stress, poor nutrition, or lack of sleep

Kurrle E, Ehninger G, Freund M et al (1986) Age adapted induction and intensified consolidation therapy in acute myelogenous leukemia