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2.3 Drug treatment schedule A cohort of 40 female rats was randomly allocated into four diverse groups, each consisting of 10 rats: Control, DXN, TIR, and DXN + TIR

Differentially expressed between tissues, SLC22A4 is notably highly expressed both on the apical membrane of the small intestine where it functions in a pH-dependent fashion to take ergothioneine up from the diet (29) and on the apical membrane of proximal tubular cells in the kidney where it functions in renal reabsorption (30)

Tudor et al., 2010) or less severe behavioral disturbances (Jelovac et al., 1998, 1999