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Description
In a study conducted using HDM-induced asthmatic mice, formononetin reduced airway inflammation by decreasing serum IgE levels and cytokines such as IL4, IL6, and IL17A, while promoting epithelial barrier repair through the inhibition of the ESR1/NLRP3/Caspase-1 signaling pathways [215]

AC: Writing original draft, Writing review & editing

The study only employed a single drug dose, overlooking dose-dependent investigations, which will also be addressed in subsequent research

By 2018, for example, there was a lively Reddit community focused on peptides