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Among them, the main antioxidant systems currently involved include: the Xc glutathioneglutathione peroxidase 4 axis (Xc GSHGPX4) (Yang et al

K.LascanoG.ParysC.HelmbrechtA.et al

-- Dual and specific inhibition of NAMPT and PAK4 by KPT-9274 decreases kidney cancer growth

However, the lack of in vivo experimental evidence makes it unclear how 5-clC and chloramine levels are regulated under physiological conditions
