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Yang et al., 2024))

Hyperglycemia drives the accumulation of advanced glycation end products AGEs, which activate the RAGE/MAPK signaling axis, thereby inhibiting Col-II synthesis and promoting a catabolic state in chondrocytes (31)

doi: 10.1016/j.jep.2024.119247 51 LiuWWangJYangHLiCLanWChenTet al

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