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While these findings suggest increased hepatic de novo gluconeogenesis, the gluconeogenic response of NKCC2A KO mice to exogenous pyruvate, which is converted into glucose in the liver, kidneys and small intestines (Stumvoll et al., 1998

Work with your provider to find strategies to manage common side effects

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While it was originally developed with therapeutic uses in mind, it remains primarily a research tool for studying fat metabolism and weight-management mechanisms
