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European journal of internal medicine, 16(6), 447-448
Normal circulating IGF-I and GHBP are fully restored only after experimental intra-peritoneal (70) or intraportal (71) insulin delivery

One of the ways to tell if B12 deficency (rather than folate deficiency) is the problem is if any of your symptoms (even tiredness) return before the next injection is due...then improve once you've had an injection

This encouraged the research for a possible action of the peptide in humans suffering from chronic pronounced pain episodes
