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Despite a careful search and selection of sources, the evidence often comes from works that were not designed to explore the field of drug-drug interactions and, in particular, with tobacco combustion compounds

Acta Physiol (Oxf) 2015;215(2):7375

Ten patients with facial melasma from India were treated with 0.05% clobetasol propionate cream topically twice daily for 4 weeks, followed by use once daily associated with sunscreen for another 4 weeks

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