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Keywords: brain regeneration, cerebellar diseases, cerebellum, innate immunity, macrophages, metabolism, microglia, neuroinflammation, neuropathology, Purkinje cells Introduction Microglia, a highly specialized subset of tissue-resident macrophages, perform well-established immunogenic functions and actively participate in neurotransmitter turnover, synaptic pruning, and release of various neuroactive factors (Grabert et al., 2016

Children with Fragile X Syndrome may experience a range of symptoms, including: Delayed development of skills such as sitting, crawling, and walking Difficulty with language and speech Behavioral issues, such as hand-flapping, poor eye contact, and temper tantrums Anxiety, depression, and obsessive-compulsive behaviors Sensitivity to light and sound Hyperactivity and attention difficulties Seizures and sleep problems In addition to these symptoms, children with Fragile X Syndrome may also have certain physical characteristics, such as a large head, long face, and loose joints