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Altered gut microbial energy and metabolism in children with non-alcoholic fatty liver disease

Additionally, the loss of GlS1 leads to -kG deficiency, and impairs the differentiation of Th17 cells [84].Glutamine uptake transporters such as ASCT2, Solute carrier family 7, member 5 (SLC7A5) and Sodium-coupled Neutral Amino Acid Transporter (SNAT), when blocked, inhibit the differentiation of CD4 + Th1 and Th17 cells [83], while SLC7A5-mediated glutamine uptake regulates the activation of c-MYC-dependent Teff cells

Molecular bases underlying the hepatoprotective effects of coffee
