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There are a number of inborn errors of metabolism that are characterised by a failure of this conjugation process, but the classical example is that of the CriglerNajjar * syndrome [5], where there are high serum levels of unconjugated bilirubin due to defects in the UDPGT gene
The extract of Salvia officinalis can significantly reduce insulin levels and the homeostasis model assessment of insulin resistance in PCOS patients, and significantly increase the quantitative insulin sensitivity check index, thus improving insulin resistance markers (64)
PLoS ONE 12 (8), e0183111
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