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Activated Smad2/3 then translocate into the nucleus, initiating transcriptional regulation of numerous fibrotic genes, triggering fibroblast phenotype transformation, promoting EMT, and significantly enhancing ECM accumulation (Peng et al., 2022
10.1177/1747519820932091 34 MuhammedM
Often during the first few years of medical school, students are taught to generalize and associate
doi: 10.1016/j.carbpol.2011.05.027
