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Pathogenic variants in POLG1 cause progressive external ophthalmoplegia (PEO) characterized by weakness of the eye muscles accompanied by other more variable symptoms

CPs are known to signal your skin to produce more collagen and elastin the proteins that keep your skin looking firm, plump, and youthful

8 A full blood count, to check for macrocytic anaemia and other haematological parameters, should also be carried out

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