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High-dose oral B12 (1,000 to 2,000 mcg daily) can actually correct deficiency even in some people with poor absorption, because a small percentage of B12 is absorbed passively (without intrinsic factor)

Each compound has its own risk profile based on its mechanism and the tissues it targets

doi: 10.1016/j.jare.2024.04.012 75 CaoSWeiYYueYChenYQianJWangDet al
