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therefore, it is speculated that the degree of arterial calcification may be related to the high concentration of TMAO ( via promoting fatty acid metabolism and mitochondrial dysfunction ( Taken together, previous studies show that TMAO can aggravate the process of atherosclerotic plaques by promoting vascular calcification

The absorption of oral L-carnitine occurs primarily in the small intestine and relies on a specific transport protein known as OCTN2

Cell 133 , 585600 (2008)