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With the water gone, the two routes that degrade glutathione, hydrolysis and oxidation, slow to a crawl, because both need a solution to proceed

A range of chemotherapeutic agents such as cisplatin, doxorubicin, paclitaxel, gemcitabine and camptothecin were attached to various fluorophores such as coumarin, cyanine, rhodol, BODIPY and naphthalimide, through a disulfide linkage to obtain glutathione-responsive drug-disulfide-fluorophore theranostic conjugates 83

Intervention mechanism of marine-based chito-oligosaccharide on acute liver injury induced by AFB1 in rats

proposed the incorporation of DL-dithiothreitol (DTT) as a bridge to form PEGDA-DTT hydrogels through the reaction between the acrylate groups of PEGDA and the thiol groups of DTT