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They are altered into the skin health
doi: 10.1016/j.jhep.2007.01.028
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The main disadvantages of CUR are the poor oral bioavailability in terms of low intestinal absorption rate, rapid metabolism, and excretion from the body [62] due to the hydrophobic (low solubility in water) and lipophilic (highly soluble in lipid) nature of CUR [63]
